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Skin Longevity
Skin Booster
A New Standard in Skin Quality Improvement
Delivering active ingredients into the skin to enhance regeneration, hydration, and elasticity
What is Skin Booster?
A SKIN BOOSTER is an advanced dermatological treatment designed to improve overall skin quality by delivering bioactive ingredients directly into the skin.
This treatment promotes Skin Regeneration, Hydration, Brightening, and Elasticity by Stimulating Collagen and Elastin production.
Active components such as hyaluronic acid, PDRN, and exosomes are administered through precise injection techniques or microneedling (MTS), ensuring effective absorption into the skin.
SKIN BOOSTER treatments are available in various formulations and should be customized according to the patient’s skin condition, concerns, and treatment goals for optimal results.
*Treatment selection and results may vary depending on individual skin condition and professional assessment.
Luxury Medical Tone
Focus: Refined Texture · Even Tone · Deep Hydration · Skin Regeneration
More Regenerative Emphasis
Focus: Skin Quality · Hydration · Elasticity · Cellular Regeneration
Focus: Skin Texture · Tone · Hydration · Regeneration
Skin Booster Treatment Plan
1
Skin Texture Reconstruction
· Focuses on improving overall skin quality
· Targets skin texture reconstruction at the epidermal and superficial dermal levels.
· Restores fundamental balance in skin texture, density, and tone.
2
Structural Skin Texture Repair
· Structural improvement and regeneration of the skin surface.
· Designed for advanced skin texture restoration, improving smoothness and clarity.
· Improves irregularity and roughness of the skin surface.
3
Skin Microtexture Restoration
· Treatments designed to improve microtexture, hydration, and overall skin quality.
· Promotes microtexture reconstruction for visibly refined skin.
· Creates a smoother and more even skin surface.
If your concern is Skin Booster…
Recommended by Age Group
Customized Skin Regeneration Treatment
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A customized skin booster treatment tailored to individual skin needs
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A fundamental treatment that enhances overall skin quality
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Restoring healthy, natural skin from within
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A regenerative solution for hydration, elasticity, and skin vitality
DERMA LONGEVITY™ NEURO-SKIN REGEN™ TIME-RESET SKIN™
INJECTABLE SERVICES
INJECTABLE FACIAL PACKAGE
REJURAN®
PN (Polynucleotide Booster)
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Salmon DNA–based skin regenerative booster
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Improves skin texture reconstruction, elasticity, and inflammation control
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Enhances overall skin quality and dermal repair
Healing Essence
with 2% Hydrolyzed DNA (High Molecular Weight)
Natural cell regeneration is supported with this anti-aging formula, while deep hydration promotes a healthier-looking complexion. Natural skin beauty effects include a more youthful appearance as the signs of aging are reversed, a visibly smoother texture is improved, and the look of damaged skin is reduced.
What is Hydrolyzed DNA?
> DNA fragments extracted from wild salmon made possible by PharmaResearch's patented technology, DOT ™
> Clear, colorless viscous solution
> Long-lasting while maintaining uniform structure in tissue
Effects of Hydrolyzed DNA
> Proven to be the most compatible with human skin (95% similarity) without adverse effects.
> Stimulates skin’s own reparative and restorative capabilities
> Improves skin turnover cycle.
> Skin elasticity improved by recovering the optimal biological condition of the dermis and epidermis.
> Reduces inflammation to alleviate skin irritation
> Reinforces skin's own barrier function
> Reduces the appearance of fine lines and wrinkles
> Helps increase and retain moisture for glowing skin
Wild Salmon (Korea)
Hydrolyzed DNA
Medical Device
Topical Sterillzed Solution
Hydrolyzed DNA Clinical Studies
The experimental group and control group were randomly assigned to compare the efficacy for 16 weeks:
Experimental group: Fractional laser + REJURAN
Control group: Fractional laser + Saline
The Vancouver Scar Scale (VSS), global photographic assessment, and objective scar were assessed using 3D camera at baseline and after surgery
The Vancouver Scar Scale (VSS), global photographic assessment, and objective scar were assessed using 3D camera at baseline and after surgery
BEFORE
AFTER 16 WEEKS
PN INJECTED GROUP
PN INJECTED GROUP
CONTROL GROUP
10 Solutions to Look 10 Years Younger
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Skin lifting effect
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improves skin elasticity
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Improves skin texture & Tone
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Reduces the appearance of fine lines & wrinkles
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Skin barrier regeneration
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Balance control of kin oil & moisture
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Minimizes pores
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Reduces sebum, oil, secretion
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Reduces dead skin cells
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Clinically proven safe
HEALING ESSENCE
with 2% Hydrolyzed DNA (High Molecular Weight)
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Excellent Recovering Effect
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Improvement of Skin Elasticity and Appearance of Fine Wrinkles
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Natural Skin Beauty Effects
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Improvement of Skin Tone and Texture
How REJURAN ® Healing Essence Works
RUJURAN ® Healing Essence uses the latest DOT ™ innovation from South Korea and is formulated with 2% Hydrolyzed DNA (High Molecular Weight) for skin rejuvenation. It is delivered into the dermis to support the skin's natural growth factors, thus promoting cellular turnover and collagen production, improving microcirculation and anti-inflammation. Rehydrates severely dry skin and enhances the skin's natural barrier for more luminous, translucent-looking skin.
What Can You Expect After the Treatment
SKIN TEXTURE > SKIN TONE > REDNESS > OIL/MOISTURE BALANCE > FINE WRINKLES > TIGHTNESS > PORES
1ST SESSION
3-5 DAYS AFTER
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Improved skin
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Restores skin balance
2ND SESSION
2-4 WEEKS AFTER
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Improved skin tightness
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Reduced appearance of fine lines and wrinkles
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Minimized pore size
3RD SESSION
4-6 DAYS AFTER
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Natural skin lifting effect
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Volumizing effect with restored dermis
TONE-UP BOOSTER
Simultaneouslyworks to strengthen the skin's natural barrier and bring brightness to the skin.
Brighten
UP AND REVIVE SKIN TONE
1
INGREDIENTS OF VIAL I
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Normalize the skin regeneration cycle and stimulate skin's own collagen production
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Replenish skin from the inside out and leave it feeling hydrated, supple and soft
1% Hydrolyzed DNA (Low Molecular Weight)
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DNA Fragments extracted from Korean wild salmon by using the patented DOT™ Technology (DNA Fragments Optimizing Technology)
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670 times smaller than skin pore size for enhanced rate of skin absorption
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A skin improvement activator reinforcing skin's own barrier function
Sodium Hyaluronate (Hyaluronic Acid)
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Humectant binds and retains water to hydrate and plump skin
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Reduces free radicals that cause premature skin aging and helps protect the skin from UV rays
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Component of the extracellular matrix (ECM), which contributes to cell proliferation and migration for re-epithelialization of skin
Panthenol
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A superb skin softener known for its moisturizing and soothing properties
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Same biological activity as Vitamin B5, which is essential for normal metabolism and hormone production
2
INGREDIENTS OF VIAL II
Composed of 3 ingredients, combined in an effective ratio, with an exceptional brightening effect. Visibly reduces the appearance of tyrosinase activity and melanin production and its accumulation
Ascorbic Acid
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Known as Vitamin C, key to the production of collagen and elastin in the skin
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Essential nutrients required for neurotransmitter function with preventative benefits
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It helps to improve the appearance of wrinkles, uneven skin tone, and moisture.
Glutathione
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Triptide consists of 3 amino acids (Glycine, Glutamic Acid and Cysteine)
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Mediates the pheomelanin production and regulates collagen production
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GSH prepared with Hyaluronic Acid reduced its four color
Tranexamin Acid
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Inhibits melanogenesis by activation of the autophagy system mediating a decrease in melanin synthesis by alleviating the production of tyrosinase, TRP1/2, and MITF protein
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Excellent skin tone-up effect, maximizes the outcome using MTS in combination
Skin Elasticity Restoration
DOT ™ Hydrolyzed DNA in REJURAN ® products restores the appearance of thinned, damaged skin and improves elasticity, resulting in a visible regenerated epidermis and dermis
SKIN BOOSTER
Pamper & Rejuvenate Your Skin with Our Advanced Mesotherapy Solution REJURAN ® SKIN BOOSTER
+ PDRN
Skin Improvement Activator
Cosmetic PDRN
+DNA fragment extracted from Korean wild salmon by using DOT ™ (DNA Optimizing Technology)
+ Skin improvement activator reinforcing skin's own barrier function
+ 670 time smaller than skin pore size for enhanced rate of skin absorption
+ Proven PDRN safety and efficacy in more than 2,000 scientific journals and 7 medical centers over the world
+ HA
Effective Hydrating Ingredient Enhancing Effect of PDRN
Hyaluronic Acid
+ Functions to retain water for your skin ti be hydrated and plump
+ Reduced free radicals that result in skin aging and protect the skin from UV rays
+ Component of the ECM, contributed to cell proliferation and migration for the re-epithelialization of the skin
+ AMINO ACID
Essential Composition Collagen and Elastin
4 Types of Amino Acid
Glucine + L-Lysince + L-Leucine + L-Proline
+ Contains Glysine and Proline essential components of collagen, which accounts for 80% of the dermis layer
+ Helps maintain and build skin collagen you lose every year with aging
+ Contains Glucine, Proline, and Leucine the components of elastin fibers in the dermis layer, for keeping your skin healthy
+ Contains the essential amino acid of Lysine and Leucine that are now made by the body to help proteins syntheis
REGENERATIVE COMPLEX
EXOSOME
KEY INGREDIENTS
16 Growth FactorGrowth Factor + Peptides
1 Peptides
1 Vitamin
5 Minerals
3 Humectants
19 Amino Acids
4 Coenzymes
SCIENCE & TECHNOLOGY OF EXOSOMES
What are Exosomes?
BENEV Exosome treatments are based on the most cutting edge scientific biotech breakthrough for skin rejuvenation and regeneration. Exosomes are responsible for cell to cell communication and for facilitating the exchange of RNA and other important proteins between cells (e.g. fibroblasts, keratinocytes, immune cells, etc.), in addition to transferring numerous growth factors and cytokines and genetic materials that have shown signs of tissue repair and improving skin cells. These data coding avatars have been harnessed for our new line of exosome products to promote a more radiant youthful appearance.
What is the function of Exosomes?
The major role of exosomes is to carry the information by delivering various effectors or signaling molecules between specific cells.
What is EXOSCRT™ ?
Exosome, an 30~200 nm endoplasmic reticulum that is secreted for cell-to-cell communication, plays an important role in influencing the microenvironment around cells, ExoSCRT™ is an innovative technology to separate and refine 0.1% pure exosomes from stem cells and helps the virtualization of natural skin energy by affecting skin cells effectively.
BENEV Exosome Regenerative Complex powered by Exo-SCRT ™ and BENEV Exosome Regenerative Complex + powered by Exo-SCRT™ are post care “topical use” cosmetic solutions. The isolated and purified exosomes in both products have been accepted by the PCPC, and International Cosmetic Ingredient Nomenclature Committee (INC), and the name ‘Human Adipose Stromal Cell Exosomes’ was given and published in the International Cosmetic Ingredient Dictionary and Handbook, known as INCI book. There are at this time no other cosmetic INCI name(s) assigned to exosome products in the market prior to this accomplishment. These products are not drug products. They are not intended to prevent, treat or cure diseases or medical conditions. They are not intended to be injected or delivered intravenously.
Exosome Regenerative Complex
Exosome Regenerative Complex is an intensive dual-action complex formulated to absorb quickly into the skin delivering the concentrated power of STEM CELL DERIVED LYOPHILIZED EXOSOMES, potent GROWTH FACTORS, PEPTIDES, COENZYMES, MINERALS, AMINO ACIDS, and VITAMINS. Our paraben-free, steroid-free, and hypoallergenic patented technologies and ingredients are clinically proven to rejuvenate the skin.
IN VITRO TESTING
Human Fibroblast Cell Proliferation
Exosome Regenerative Complex and Exosome Regenerative Complex + powered by ExoSCRT™ promotes skin cell proliferation by up to 80% in a dose-dependent manner. ExoSCRT™ 3 µg/ml 36.1% increase, ExoSCRT ™ 6 µg/ml 84.0% increase, compared against positive control (1% GS).
NEGATIVE CONTROL
1% GROWTH SUPPLEMENTS
1% GS + ERC 3 uG/ML
1% GS + ERC 6 uG/ML
Elastin Increased by ExoSCRT ™
Exosome Regenerative Complex and Exosome Regenerative Complex + powered by
ExoSCRT ™ may increase the elastin amount of human dermal fibroblasts up to 300% in vitro.
Collagen Increased by ExoSCRT ™
After delivery of BENEV Exosome Regenerative Complex and Exosome Regenerative Complex + powered by ExoSCRT ™ into fibroblasts, neocollagenesis can increase up to 6 folds.
Cellular Uptake of EXOSOMES
Human skin cells easily uptake BENEV Exosome Regenerative Complex and Exosome Regenerative Complex + powered by ExoSCRT ™ which means that stem cell-derived exosomes can message skin cells to “Do Something”.
EXOSOME
REGENERATIVE COMPLEX
SKIN
Noticeably reduces the appearance of age-related pigment Visibly makes skin appear firmer and more youthful Visibly reduces the appearance of fine lines and wrinkles Hydrates and nourishes the skin Promotes a more radiant and even-toned complexion
SCALP
Noticeably reduces the appearance of age-related pigment Visibly makes skin appear firmer and more youthful Visibly reduces the appearance of fine lines and wrinkles Hydrates and nourishes the skin
EXOSOME
REGENERATIVE COMPLEX +
99%
PURE
EXOSOME
INCREASE IN
FIBROBLAST
180%
INCREASE IN
ELASTIN
300%
BEFORE & AFTER
POST MICRO NEEDLING
Female | 28
Photo Provided by:
Dr. Diane Duncan .,MD.,F.A.C.S
POST MICRO NEEDLING
Female | 35
Photo Provided by:
Dr. Richard Jin., MD., PhD
POST MICRO NEEDLING
Female | 49
Photo Provided by:
Dr. Richard Jin., MD., PhD
POST MICRO NEEDLING
Female | 49
Photo Provided by:
Dr. JD McCoy NMP
Patient trial photos (Mei Vu™) were taken before and after a 3 - 5 EXO-XOM FACIAL Clinical Study featured BENEV Exosome Regenerative Complex powered by ExoSCRT TM. Participants experienced no irritation, and all patients reported that they felt and saw a noticeable and immediate difference in the overall appearance of their skin after just the first treatment, with full results after the 3rd-5th treatment.
POST MICRO NEEDLING
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Protocol: 1 week interval, 5 sessions
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Improvement of hairline and growth of baby hair on the top of the head
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Clinical conducted by : Dr. Hwang HeuiLee, Cheongdam NB Clinic
POST MICRO NEEDLING
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Protocol: 2 sessions of treatments (a day before the hair implantation and during the hair implantation)
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Patient’s satisfaction index : 10 (out of 10). Product was applied on where hair was collected, and it has improved bleeding and redness.
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Clinical conducted by : Dr. Asli Berker
POST MICRO NEEDLING
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Protocol: 1-month interval
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Effective in the hair loss (Hair Restoration)
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Clinical conducted by : Pure Vanity Spa
POST MICRO NEEDLING
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Protocol: 1 week interval, 5 sessions
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Improvement on the overall hair loss and that of the top of the head
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Clinical conducted by : Dr. Chang Ro Lee, Leo Clinic
POST MICRO NEEDLING
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Protocol: 2 sessions of treatments (a day before the hair implantation and during the hair implantation)
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Patient’s satisfaction index : 10 (out of 10). Product was applied on where hair was collected, and it has improved bleeding and redness.
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Clinical conducted by : Dr. Asli Berker